How fast does Accutane 40 mg work? https://www.dosepharmacy.com/tretiva-40mg-capsule Accutane (isotretinoin) is a powerful medication used to treat severe acne. It works by reducing the production of oil and sebum in the skin, and by killing the bacteria that cause acne. Accutane is typically taken for 4-6 months, and it can start to work within 2-3 months. However, it may take up to 6 months to see the full results. It is important to be patient and to continue taking the medication as prescribed by your doctor.