PHILADELPHIA - The wear and tear of the NFL season is finally catching up to the Eagles, at least a little bit.Philadelphia, the only undefeated team left in the league at Ryan Broyles Jersey 3-0, officially ruled out running back Boston Scott (rib), and slot cornerback Avonte Maddox (ankle) for Sundays game against Doug Pederson and the 2-1 Jacksonville Jaguars.The Scott news was expected after the veteran running back mi sed practices on Wednesday and Thursday and head coach Nick Sirianni gave the heads up before Fridays light practice se sion at Lincoln Financial Field that Scott again mi sed.Trey Sermon, who was picked up off waivers from San Francisco on Sept.1, is expected to be active for the first time as an Eagle."I'm really excited. I know they brought me here for a reason, Sermon told the Eagles website. ... I've been caught up to speed and getting the reps in practice, getting more comfortable with the offensive linemen getting in sync. It's been good for me."Scott has played 36 offensive snaps (12 per game) over the first three games and has 11 touches (10 runs and 1 reception) so Sermon is surely not in line for a big role behind Miles Sanders and Kenny Gainwell.In fact, coach Nick Sirianni could simply lean more on his top two runners if he likes, although Sanders was dealing oshua Dobbs Jersey with a hip i sue earlier in the week before being listed as a full participant at both Thursday and Fridays practices.The far bigger i sue is Maddox, who turned his ankle at practice on Thursday, according to a team source.Maddox is e sentially a starter in the teams slot cornerback position, playing 87% of the defensive snaps over the first three games. The Pitt product is also performing at a very high level, being graded out as No. 6 of the 101 CBs who have played enough to be ranked by Pro Football Focus.Scroll to ContinueMeanwhile, Jacksonvilles top receiver Christian Kirk, who has 18 receptions for 267 yards and three touchdowns, spends most of his time in the slot. Kirk, who signed a big-money deal in free agency, has played 198 offensive snaps with 126 of them coming inside so Maddox was set to be tasked with shutting down the shifty receiver who PFF has graded as No. 22 of 103 WRs.The Eagles could go a number of different ways when it comes Wisconsin Badgers Jersey Sale to replacing Maddox. The most obvious would just be inserting the fourth CB, second-year man Zech McPhearson, as the slot CB inside of Darius Slay and James Bradberry. Josiah Scott, who also cro s-trained at safety this summer, is the listed backup for Maddox and is a natural slot CB.It should also be noted that before the Eagles acquired Chauncey Gardner-Johnson and moved him to safety, the veteran played slot cornerback for New Orleans and was very effective in that role.Furthermore, the top backup at safety is Also, Matt McQuaid Jersey CGJs transition to safety hasnt been without hiccups (PFF has Garner-Johnson graded as No. 64 of 72 safeties through three games). He has, however, played 100% of the defensive snaps the past two weeks. Getting him some confidence with reps at a position hes more comfortable with could be considered.Im a profe sional," he said during Thursday's open locker room se Eddie Goldman Jersey sion. "Not to be disrespectful or anything, they brought me in to do certain things. So Im going to have fun. Call the defense, call the shots. Its a whole new position for me. I think Im filling in well. I think the guys brought me in well, helped me learn. "... When youre a profe sional, you just dive into what you need to focus on. And being here for the past two games, we have the best defensive backfield in football.From a meritocracy standpoint, Gardner-Johnson is certainly the second-best option the Eagles have in the slot so defensive coordinator Jonathan Gannon and secondary coach Dennard Wilson will have to decide if CGJ at safety with McPhearson or Scott in the slot is the better alternative than Gardner-Johnson in the slot and Wallace at safety.