Vector Purification Market is Projected to Witness Significant Growth Due to Increasing Adoption of Gene Therapy

The vector purification market manufactures products that are used to purify viral vectors such as adeno-associated virus (AAV), lentivirus, retrovirus and adenovirus. These vectors are important tools for gene therapy as they help transfer therapeutic genes into targeted human cells. The purification process removes contaminants and other unwanted substances from the final vector preparation, thereby maximizing its safety and efficacy.

The vector purification market is estimated to be valued at USD 336 Mn in 2024 and is expected to reach USD 1,300 Mn by 2031, growing at a compound annual growth rate (CAGR) of 21.3% from 2024 to 2031.

Increasing research on gene therapy and growing demand for viral vectors from biopharma companies are fueling market growth.

Key players operating in the vector purification market are Merck KGaA, Thermo Fisher Scientific Inc., Danaher Corporation, Sartorius AG, General Electric Company, and Lonza.

Key opportunities: Increasing R&D investments by governments and pharmaceutical companies in gene therapy and cell therapy are creating lucrative opportunities for players in the Vector Purification Market. Additionally, growing number of clinical trials for various applications such as cancer, genetic disorders are expected to boost demand.

Technological advancements: Continuous innovations are occurring in vector purification technologies such as improved chromatographic methods, novel resins and affinity ligands which can significantly increase vector yield and purity. Introduction of automated closed systems is further enhancing process scalability and productivity.

Market drivers

Growing gene therapy industry: Successful approvals and commercialization of gene therapies in recent years have augmented the demand for viral vectors. This in turn is fueling the need for efficient and optimized vector purification systems to manufacture high volumes of gene therapy products. Factors such as supportive regulations and healthcare reimbursements are further propelling the gene therapy sector.
Challenges in Vector Purification Market

The vector purification market is growing at a rapid pace. However, there are a few challenges that are hampering the growth potential of this market. One of the major challenges is the availability of skilled professionals who can handle sophistical vector purification instruments. Since these instruments use advanced technologies like chromatography, skillful operators are required to run the processes efficiently. Lack of trained manpower is leading to inefficiencies in some operations. Another challenge is the high costs associated with vector purification processes. Some advanced techniques like ion-exchange chromatography require expensive resins and membranes. This increases the production costs. Finally, stringent regulations around vector purification are also a hindrance. Regulatory frameworks around vector characterization, manufacturing, and quality control are quite complex. Meeting all regulatory standards demands significant investments and manpower.

SWOT Analysis
Strength: Advanced vector purification techniques like affinity chromatography offer high selectivity and yield. Capable of isolating complex protein fragments.
Weakness: Require substantial capital investments in setting up purification facilities. Processes can be time-consuming.
Opportunity: Growing cell and gene therapy sector will boost demand. Increasing R&D in DNA vaccines and immunotherapy creates scope.
Threats: Competition from emerging players offering cost-effective solutions. Stringent quality norms may delay product approvals.

Geographical regions of concentration
North America currently accounts for the largest share of the global vector purification market, both in terms of value and volume. This is attributed to presence of major industry players and strong R&D funding for vaccine and cell therapy development in the US.

Fastest growing region
Asia Pacific region is expected showcase fastest growth over the coming years. Factors such as expanding biopharma industry, increasing healthcare investments, and rising disease incidence will support market growth in China and India. China, in particular, is an emerging country for vaccine manufacturing and is witnessing heavy investments in this field.

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Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. (https://www.linkedin.com/in/ravina-pandya-1a3984191)

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5 Vector Purification Market is Anticipated to Witness High Growth Owing to Rising Prevalence of Genetic Disorders

Vector purification refers to the process of isolating viral or non-viral vectors from biological substances based on physical and chemical properties such as size, density, solubility or reactivity. The process is essential for manufacturing vectors used in gene and cell therapy applications. The market has been witnessing significant growth due to the increasing prevalence of genetic disorders and growing demand for gene and cell therapies. Gene therapies are becoming mainstream treatment option for various rare diseases like hemophilia, lysosomal storage disorders, retinal disorders and muscular dystrophies which is driving the need for vectors.
The vector purification market is estimated to be valued at USD 336 Mn in 2024 and is expected to reach USD 1,300 Mn by 2031, growing at a compound annual growth rate (CAGR) of 21.3% from 2024 to 2031.

Key players operating in the Vector Purification Market are Merck KGaA, Thermo Fisher Scientific Inc., Agilent Technologies, Danaher, Bio-Rad Laboratories, Inc., QIAGEN, Takara Bio Inc., Lonza, General Electric, and Sigma-Aldrich Corporation.

The key opportunities in the market include rising research funding for gene therapy and cell therapy, Vector Purification Market development of next generation advanced therapies and focus on contract service providers for large-scale GMP manufacturing.

Major market players have been actively expanding globally especially in regions with high biotechnology and pharmaceutical industries like North America and Europe through collaborations and acquisitions to leverage market opportunities.

Market Drivers

Increasing research activities for cell and gene therapies: There has been substantial increase in funding for research studies on gene and cell therapies. Several clinical studies are being conducted for rare genetic diseases which is expected to drive the need for high quality and high volume vector purification systems.

Advancements in vector manufacturing platforms: Significant progress has been made towards the development of scalable and efficient manufacturing platforms for viral and non-viral vectors. Continuous flow systems and automated closed systems for vector production and purification are being adopted to achieve high yields.

Market Restrains

High cost of instruments and low adoption in emerging markets: Vector purification instruments requiring advanced chromatographic techniques are highly expensive. This acts as a major barrier especially in price sensitive emerging markets.

Stringent regulatory frameworks: Vector manufacturing is a highly regulated process and requires production to be done under cGMP certified facilities. Obtaining regulatory approvals is a long and costly process which hinders market growth.

Segment Analysis
The global vector purification market is segmented on the basis of product, method, application and end-use. Based on product, the market is categorized into kits, reagents, instruments. Among these, the kits segment dominates currently and is expected to maintain its dominance over the forecast period. Kits are one-step solutions for vector purification that offer high purity and yield which drives its adoption.

Based on method, the market is classified into column-based methods, precipitation-based methods and other methods. The column-based methods hold a substantial share as they are scalable, convenient and provide high yield and purity. Application-wise, the vector purification market is divided into therapeutic applications, research applications and other applications. Therapeutic applications hold the largest share owing to rising demand for gene and cell therapies.

In terms of end-use, the market covers academic and research institutes, pharmaceutical and biotechnology companies and other end-users. Pharmaceutical and biotechnology companies are leading end-users of vector purification products due to wide application of vectors in drug development and rising number of biopharmaceutical companies conducting research.

Global Analysis
Regionally, North America dominates the global vector purification market and is expected to continue its leadership over the forecast period. This is attributed to increasing research funding by government bodies such as NIH for gene therapy development, growing pharmaceutical industry and high adoption of advanced technologies. Europe holds the second largest share driven by growing focus on enzyme engineering and genetic testing. Asia Pacific is projected to witness highest growth owing to expanding pharmaceutical industry in emerging economies such as China and India. Robust penetration of Western pharmaceutical players in countries like India and China also supports market growth in Asia Pacific.

Get this Report in Japanese Language: ベクター精製市場

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About Author:

Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. (https://www.linkedin.com/in/ravina-pandya-1a3984191)