Preparative And Process Chromatography Industry Overview

The global preparative and process chromatography market size was estimated at USD 9.5 billion in 2022 and is anticipated to grow at a compound annual growth rate (CAGR) of 9.08% over the forecast period.

The growth of this market is driven by the rising demand and approval of monoclonal antibodies in the pharmaceutical and biotechnology sectors. In addition, the market is driven by the expanding biopharmaceutical industry, the demand for advanced purification techniques, and the need for more efficient and cost-effective processes. Technological advancements and the development of innovative chromatography products are expected to boost market growth. For instance, in October 2021, CEM launched the prodigy preparative high-performance liquid chromatography (HPLC) system.

Gather more insights about the market drivers, restrains and growth of the Preparative And Process Chromatography Market

A chromatography system is a scientific technique used for isolating specific components from sample mixtures. Analytical and preparative chromatography systems are widely employed in qualitative and quantitative methods to analyze biotechnological, pharmaceutical, and other components. The market for chromatography systems is experiencing growth due to various factors, including the increasing demand for insulin and omega-3 fatty acids, rising concerns related to food quality & safety, and the growing geriatric population. Moreover, ongoing research paradigms focusing on the separation and analysis of monoclonal antibodies using mild reverse-phase chromatography are expected to drive research in this market.

Companies are actively involved in developing flexible and robust platforms for the continuous production of monoclonal antibody products, leading to an increased demand for quality control measures. The market is experiencing growth due to the high demand for preparative techniques, technological advancements in chromatography, and the large-scale integration of liquid chromatographic techniques in downstream processing. Affinity chromatography has emerged as a pivotal tool to purify proteins as it is based on highly specific interactions occurring between the protein of interest and an immobilized ligand.

The Downstream Process (DSP) or the product purification process is one of the costliest aspects of modern bioprocess protocols, particularly with respect to proteins. Hence, in these cases, chromatography serves as a crucial tool at all stages of DSP, from early initial capture to the final polishing or finishing steps. Preparative techniques have gained wide acceptance for the purification of APIs and the key drivers associated with this expanding acceptance include improved throughput, cost-effectiveness, and purity. These techniques offer the users sufficient material volume at the desired quality for the initiation of clinical and preclinical trials. This, in turn, opens alternative routes for commercialization with minimum time invested in product development.

Browse through Grand View Research's Biotechnology Industry Research Reports.

• The global insulin market size was estimated at USD 20.35 billion in 2021 and is expected to expand at a compound annual growth rate (CAGR) of 1.5% from 2022 to 2030.
• The global biotechnology market was valued at USD 1.55 trillion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 13.96% from 2024 to 2030.

Preparative And Process Chromatography Market Segmentation

Grand View Research has segmented the global preparative and process chromatography market based on product, type, end-use, and region:

Preparative And Process Chromatography Product Outlook (Revenue, USD Million, 2018 - 2030)

• Process Chromatography
  • System
  • Consumables
  • Service
• Preparative Chromatography
  • System
  • Consumables
  • Columns
  • Service

Preparative And Process Chromatography Type Outlook (Revenue, USD Million, 2018 - 2030)

• Liquid Chromatography
• Gas Chromatography
• Thin Layer Chromatography
• Paper Chromatography
• Gel-permeation (Molecular Sieve) Chromatography
• Hydrophobic Interaction Chromatography

Preparative And Process Chromatography End-use Outlook (Revenue, USD Million, 2018 - 2030)

• Pharmaceutical
• Biotechnology
• Food
• Nutraceutical
• Others

Preparative And Process Chromatography Regional Outlook (Revenue, USD Million, 2018 - 2030)

• North America
  • US
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Sweden
  • Denmark
  • Norway
• Asia Pacific
  • Japan
  • China
  • India
  • South Korea
  • Australia
  • Thailand
• Latin America
  • Brazil
  • Mexico
  • Argentina
• Middle East Africa (MEA)
  • South Africa
  • Saudi Arabia
  • UAE
  • Kuwait

Key Companies profiled:

• GE Healthcare
• Danaher Corp.
• Merck KGaA
• Bio-Rad Laboratories Inc.
• Thermo Fisher Scientific Inc.
• Shimadzu Corp.
• Agilent Technologies
• Waters Corp.
• Novasep Holding S.A.S

Key Preparative And Process Chromatography Company Insights

Companies engaged in the development of innovative products are expected to intensify the market competition. The key players are focused on continuous innovations and launching products to retain and acquire market share. Moreover, the companies are developing products as per the global demands, along with the integration of advanced technologies in the product. For instance, in August 2020, the new Thermo Scientific Dionex Easion ion chromatographic system was launched by Thermo Fisher Scientific for water analysis. This product support reduces the total cost of maintenance and ownership. In November 2020, Shimadzu Corporation launched the “Advanced i-Series” HPLC. This is an improved flagship LC model to support remote work.

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