Europe PDX models Market which was USD 48002.80 thousand in 2022, is expected to reach USD 162882.33 thousand by 2030, at a CAGR of 16.5% during the forecast period 2023 to 2030.

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Pancreatic cancer (PC) remains a highly lethal cancer, which still requires profound clinical and preclinical research. The predictive power of patient-derived xenograft (PDX) model determines that it will become an important tool for preclinical and clinical research. PDX is not only widely used in preclinical studies of PC drugs, but also can be used to predict the result of human clinical trials. The PDX model and the corresponding patients’ co-clinical trial can quickly obtain the drug response, optimize the combination, explore drug resistance mechanisms, and screen for biomarkers. Meanwhile, PDX can be used for personalized medicine as patient’s avatar model. With the development of novel PDX models: patient-derived orthotopic xenografts (PDOX) model, humanized PDX model and CTC-derived PDX model, cooperation of various research teams is needed to build PDX encyclopedia of PC.

Type

• Mice Models
• Rat Models

Tumor Type

• Gastrointestinal Tumor Models
• Lung Tumor Models
• Haematological Tumor Models
• Gynecological Tumor Models
• Respiratory Tumor Models
• Urological Tumor Models
• Others

Application

• Preclinical Drug Development
• Precision Medicine
• Co-Clinical Trials
• Basic Cancer Research
• Biomarker Analysis
• Oncology Research

Technique

• Heterotopic Implantation
• Orthotropic Implantation

End User

• Academic and Research Organizations
• Contract Research Organizations
• Pharmaceutical and Biotechnological Companies
• Others

Patient-Derived Xenograft / PDX Model Market Advantages:

• Clinical Relevance: PDX models closely mimic the genetic and histological characteristics of human tumors, providing researchers with a more accurate representation of disease progression and treatment responses compared to traditional cell line models. This enhances the translational potential of findings from preclinical studies to clinical applications.
• Heterogeneity Preservation: PDX models maintain the intratumoral heterogeneity observed in patients' tumors, allowing researchers to study diverse cell populations within a single model. This mirrors the complexity of cancer biology and aids in understanding mechanisms of resistance and response to therapies.
• Personalized Medicine: PDX models can be established from individual patient samples, enabling researchers to test the efficacy of various treatment regimens on a patient-specific basis. This facilitates the development of personalized treatment strategies tailored to a patient's unique genetic makeup and tumor characteristics.
• Drug Development and Screening: PDX models serve as valuable tools for evaluating the effectiveness of new drugs and therapies before clinical trials. This enables researchers to identify promising compounds and eliminate less effective ones early in the drug development process, saving time and resources.
• Biomarker Discovery: PDX models facilitate the identification of biomarkers associated with treatment response or resistance. This assists in selecting patients who are most likely to benefit from specific therapies and enables the development of companion diagnostics.

 

 

 

Highlight of Table of Content:

§  Chapter 1: Market overview

§  Chapter 2: Europe PDX models Market Analysis

§  Chapter 3: Regional analysis of the Europe PDX models Market

§  Chapter 4: Market segmentation based on types and applications

§  Chapter 5: Revenue analysis based on types and applications

§  Chapter 6: Market share

§  Chapter 7: Competitive Landscape

§  Chapter 8: Drivers, Restraints, Challenges, and Opportunities

§  Chapter 9: Gross Margin and Price Analysis

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Some of the major players operating in the patient derived xenograft (PDX) models market are:

• Crown Bioscience Inc. (U.S.)
• THE JACKSON LABORATORY (U.S.)
• Champions Oncology, Inc. (U.S.)
• Charles River Laboratories (U.S.)
• Wuxi AppTec (China)
• Oncodesign (Canada)
• Aragen Bioscience (India)
• Biocytogen (U.S.)
• Bioduro (U.S.)
• Creative Animodel (U.S.)
• Covance Inc. (U.S.)
• EPO Berlin-Buch GmbH (Germany)
• EUROPDX. (Belgium)
• Explora BioLabs (U.S.)
• Hera BioLabs (U.S.)
• Horizon discovery Ltd. (U.K.)

Profound Questions Answered in this Report:

·        What is the growth rate of various stages in the value chain of the industry?

·        Which region has the highest growth rate and size of the emerging market by value in 2022?

·        Who are the competitive players in Europe PDX models Market?

·        Which region has the largest share and degree of competition in the industry?

·        What is the CAGR of the market during the forecast period 2023 to 2030?

·        Which region is expected to hold the highest market share for the market?

·        What is the main driver of the Global Patient Derived Xenograft (PDX) Models Market?

·        What is sales volume, revenue, and price analysis of top players of the market?

·        What are the market opportunities and threats faced by the vendors in the industry?

·        What has been the impact of COVID-19 on the Europe PDX models Market?

 

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